HOW TO TAKE KETAMINE TROCHES
How to take ketamine troches. Ketamine troches, also known as sublingual ketamine lozenges, are a popular option for patients to use ketamine at home to treat chronic pain, depression, or anxiety. While they are effective, many patients in the United States struggle to obtain clear instructions on how to use ketamine troches correctly.
What Is a Ketamine Troche?
A ketamine troche is a square-shaped, easily dissolved tablet that is put beneath the tongue or between the cheek and gum. It slowly delivers ketamine into your circulation via the oral mucosa (mouth lining), bypassing the digestive system and improving absorption.
Step-by-Step: How to Take Ketamine Troches
- Wash your hands before handling the troche.
- Do not eat or drink for 15–30 minutes before taking it.
- Place the troche under your tongue or between your cheek and gums.
- Let it fully dissolve—this may take 10 to 15 minutes. Do not chew or swallow it.
- Avoid talking or swallowing during the process to maximize absorption.
- After it dissolves, wait at least 30 minutes before eating or drinking.
How Long Does It Take to Feel Effects?
Effects normally start within 15–45 minutes and can continue between 60–120 minutes. You should feel relaxed, possibly “floaty,” with improved mood or pain alleviation. Do not drive or handle machinery during or after your dose until fully recovered.
Common Dosage Info
Your dose is prescribed by your provider, but typical ketamine troche dosages range from
25 mg to 200 mg per dose
Often taken once every few days, depending on your condition
Start low, go slow, and always follow your prescriber’s exact instructions.
Note: Ketamine is a Schedule III substance that should be used only under medical supervision. For more information on dosage click here
Safety Tips When Taking Ketamine Troches
Have a trusted person nearby for your first dose at home
Avoid alcohol, cannabis, or other CNS depressants
Store your ketamine lozenges safely away from children or pets
Report side effects like nausea, confusion, or prolonged sedation to your provider
What If the Troche Doesn’t Fully Dissolve?
It’s fine if a small amount remains. Once the bulk has dissolved, gently swish and consume it. However, do not chew, as chewing lowers the troche’s potency.
Knowing how to take ketamine troches correctly can help make your therapy safer and more effective. Follow your provider’s recommendations, avoid distractions when dosing, and monitor how you feel after each dose.
If you are unsure about anything, see your compounding pharmacy or ketamine supplier. You are not alone; more and more patients are utilizing sublingual ketamine as part of their rehabilitation process.